CRPS Treatment: pain in both feet for 3 years

General details and patient's info

Gender:Male.
Age:60 years old at the time of treatment.
Home Country:United States of America.
Illness duration:3 years prior to the Neridronate Treatment.
Cause:Important fall at work.
Symptoms:Constant sharp pain, swelling. Walking and standing trigger more pain, difficulty to walk, burning sensation. The patient needs to use ice patches continuously on his feet.
Clinical evaluation:Complex Regional Pain Syndrome.
Time of treatment:May 2024.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient was under several medications and had tried Ketamine infusions with very little results. His wife, working as a medical accounting, was able to research and enquire among several doctors and discovered the Italian treatments for CRPS. They booked their flight to Venice shortly after.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

3 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep + 45 minutes in the morning).
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Meeting with the Nutritionist.

Meeting with the Health Coach.

Daily Report

DAY 1: Arrival at Venice airport greeted by his patient manager, check in at Venice hotel, briefing on the treatment week.

DAY 2: Rest day, in contact with his patient manager.

DAY 3: Pick-up by his patient manager and check out the hotel. Full tourism day in Venice, and in the evening, check in at the Verona Hotel. Light therapy and biophysical treatment in his room.

DAY 4: Rest day, in contact with his patient manager. Light therapy and biophysical treatment in his room.

DAY 5: Rest day, in contact with his patient manager. Light therapy and biophysical treatment in his room.

DAY 6: Pick-up by his patient manager, blood tests, first visit with rheumatologist, first rehabilitation session, first infusions. In the afternoon the patient underwent the Dexa-Scan. Light therapy and biophysical treatment in hotel room.

DAY 7: Pick-up by his patient manager, meeting with the nutritionist, and second infusions. In the afternoon, after lunch in typical restaurant, meeting with the health coach for some tests and an evaluation of his condition. Light therapy and biophysical treatment in hotel room.

DAY 8: Pick-up by his patient manager, second rehabilitation session and third infusions. Today the patient feels a bit nauseous, in the afternoon he rests at the hotel. Light therapy and biophysical treatment in hotel room.

DAY 9: Rest day, in contact with his patient manager. Light therapy and biophysical treatment in his room.

DAY 10: Pick-up by his patient manager, second visit with the rheumatologist, third rehabilitation session, fourth infusions and last meeting with the health coach. Light therapy and biophysical treatment in his room.

DAYS 11-12: Rest day, in contact with his patient manager. Light therapy and biophysical treatment in his room.

DAY 13: Pick-up by his patient manager, check out and drop off Venice airport for the flight back home

Follow up

JUNE 2024 (2 months post-treatment): the pain has not yet improved, but his feet do not turn red and bright anymore. The patient sees some progress and alternates good and bad days.

JULY 2024 (3 months post-treatment): the patient says that the nothing changed in the past month.

AUGUST 2024 (4 months post-treatment): the patient mentions his feet feel much better and he reports a 50% general improvement of symptoms.

Ongoing follow-up.

Conclusion

This patient could take advantage of the 360° treatment plan and was supported by several medical professionals at MTI clinic: rheumatologist, nutritionist, physiotherapist, personal health coach, nurse, pharmacist. All together they provided, beside the Neridronate treatment, a very tailored plan around him. It is important that the patients follow the suggestions they receive here after they go home, to speed the recovery and learn a correct lifestyle.
Some patients will see results after a few weeks, other will see most of the results after a few months: everyone is different. This is an ongoing follow-up, and we still are hoping for even further results.

DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.