CRPS Treatment: pain in both hands for 3 years

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CRPS Treatment: pain in both hands for 3 years

Contents

General details and patient's info

Gender:Female.
Age:26 years old at the time of treatment.
Home Country:Canada.
Illness duration:3 years prior to the Neridronate Treatment.
Cause:Her hands were crushed by a falling box at home.
Symptoms:Even though there were no fractures, the patient’s hands swelled up a few hours after the injury and pain started immediately. Burning and sharp pain, worse on the left hand than on the right. Highly sensitive to touch and temperature changes. Occasionally she has spasms on the left hand.
Clinical evaluation:Complex Regional Pain Syndrome.
Time of treatment:January 2024.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient underwent desensitization treatments and physiotherapy, which helped a bit but not enough to be able to use her hands freely for everyday activities. She was under a few medications to manage her pain which ranked 8 or 9 on 10, especially on her left hand. After she was forced to quit her job as an accountant because it was too painful to manage, she decided to travel to Italy because she thought it was the best option.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

2 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep + 45 minutes in the morning).
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Session with the Nutritionist.
Meetings with the Health Coach.

Daily Report

DAY 1: Arrival at Venice airport greeted by her patient manager, check in at Verona hotel, briefing on the treatment week. Light therapy and biophysical treatment in hotel room.

DAY 2: Rest day in contact with her patient manager. The patient is still tired from the flight, but she goes for a walk in Verona center. Light therapy and biophysical treatment in hotel room.

DAY 3: Pick-up by her patient manager, blood tests, first visit with rheumatologist, first rehabilitation session, first infusions. In the afternoon the patient does the Dexa-Scan. Light therapy and biophysical treatment in hotel room.

DAY 4: Pick-up by her patient manager, meeting with the Nutritionist, second infusions. In the afternoon she visits Soave village and its castle with her patient manager. Light therapy and biophysical treatment in hotel room.

DAY 5: Pick-up by her patient manager, third infusions and meeting with the health coach for some tests and a detailed evaluation of her general condition. In the evening, she feels very tired and achy, she takes some Tylenol. Light therapy and biophysical treatment in hotel room.

DAY 6: Pick-up by her patient manager, she feels better than the previous day. Second visit with the rheumatologist, second rehabilitation session, fourth infusions and last meeting with the Health Coach. Light therapy and biophysical treatment in her room.

DAY 7: Day trip to Venice with her patient manager. Light therapy and biophysical treatment in her hotel room.

DAY 8: Light therapy and biophysical treatment in her hotel room. Pick-up by her patient manager, check out and drop off Venice airport to fly back home.

Follow up

FEBRUARY 2024 (1 month post-treatment): the patient says that she occasionally she some better days, with less pain in both hands.

APRIL 2024 (3 months post-treatment): the patient says that the pain is decreasing in her right hand, still present on the left one. However, she can manage her daily needs by herself.

JUNE 2024 (5 months post-treatment): the patient reports a great decrease of the pain in both her hands. She feels more motivated to exercise according to the suggestions she received from the Italian coach and physiotherapist.

SEPTEMBER 2024 (8 months post-treatment): the patient feels much better and confident, and she is back to work. Het sensitivity has drastically lowered.

Conclusion

This is a successful case, where a young patient was able to minimize her pain and go back to her life and to her job. She was used to ask help for every basic task, such as getting dressed, eating, driving, opening a bottle: that made her dependent from others with consequences on her mood too. She mentions a general 80% improvement of all symptoms at her 8 months mark.
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.