CRPS Treatment: pain in both hands for 6 years

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CRPS Treatment: pain in both hands for 6 years

Contents

General details and patient's info

Gender:Male.
Age:60 years old at the time of treatment.
Home Country:USA.
Illness duration:6 years prior to the Neridronate Treatment.
Cause:Unknown.
Symptoms:Burning pain in both hands, going to shoulders and chest. Numbness, tingling, weakness especially in right arm. Need of help to manage simple tasks as bottles opening, cutting food, getting dressed.
Clinical evaluation:CRPS.
Time of treatment:March 2019.

Why the Patient decided to undergo the CRPS Treatment in Italy

This patient’s CRPS started without a specific trauma, surgery, fracture or other triggering events. It took a long time and a lot of different medical consultations before a doctor gave him the diagnosis. He underwent several treatments and stayed in a specialized hospital for 4 months, with just very mild and non-lasting improvements. After he went on disability from his carpenter job, he devoted himself to researching any available information on the disease and he found MTI.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

Daily Report

DAY 1: Arrival at Venice airport, together with his wife, welcomed by his Patient Manager; check in at Verona hotel and rest.

DAY 2: Rest day, in contact with his Patient Manager, to recover from the long flight.

DAY 3: Morning pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor, 1st infusions.

DAY 4: Morning pick-up by his Patient Manager and 2nd infusions. The patient says his hands are in great pain, the Professor prescribes Paracetamol.

DAY 5: Morning pick-up by his Patient Manager and 3rd infusions. The patient has a light fever and keeps on taking Tylenol.

DAY 6: Morning pick-up by his Patient Manager, last visit with the Rheumatologist Professor and last infusions. He feels a little better and the Rheumatologist gives him full information on the temporary side effects of the drug he had been feeling.

DAY 7: Day trip to Garda Lake with the Patient Manager. Fever has gone and pain levels have decreased.

DAY 8: Rest day in contact with his Patient Manager and getting ready to go back home.

DAY 9: Early pick-up from his Patient Manager, check out and drop off to Venice airport. The patient feels much better, the drug side effects are completely gone.

Follow up

JUNE 2019 (3 months after the Neridronate treatment): the patient says that he is experiencing the first improvements.

JULY 2019 (4 months after the Neridronate treatment): the patient reports a decrease of pain, he feels stronger, and he can do more things with his hands.

SEPTEMBER 2019 (6 months after the Neridronate treatment): the patient refers a decrease of pain of about 50% after his Italian stay. He does not need any more help from his wife to perform his daily activities.

Conclusion

This patient didn’t wish to follow the treatment path advised upon the evaluation of the case, and only wanted to undergo the infusions. Physical therapy sessions as well as a visit with the Nutritionist to crate a tailor-made anti-inflammatory diet would have most probably help to get further improvements than the ones he has gotten after his trip to Italy.
50% improvements of symptoms after a 6 years fight against CRPS was still a very positive outcome for this patient
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.