CRPS Treatment: pain in both legs for 1 year

General details and patient's info

Gender:Female.
Age:30 years old at the time of treatment.
Home Country:USA.
Illness duration:15 months prior to the Neridronate Treatment.
Cause:Knee injury while kickboxing.
Symptoms:Symptoms showed up 2 weeks after the initial injury. The left knee started to get swollen, it turned red and was hot to touch. The patient is a nurse, used to 12 hours shifts, standing for so long worsened her condition and the pain quickly spread to the right knee, with a tingling, burning, sharp sensation. At that point she could not stand for more than 20 minutes, couldn’t climb stairs, and eventually wasn’t able to work anymore.
Clinical evaluation:Complex Regional Pain Syndrome.
Time of treatment:May 2024.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient took medication, which was helpful in reducing the swelling, but its effect lasted only a few months. She tried physiotherapy and stretching, which helped with the range of motion but not with the pain. The patient researched further options, and she was impressed by the numerous success stories with Neridronate and 360° treatment, so she decided to take this path. 

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

2 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep + 45 minutes in the morning).
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Session with the Nutritionist.

Daily Report

DAY 1: Arrival at Venice airport greeted by her patient manager, check in at Verona hotel, briefing on the treatment week. Light therapy and biophysical treatment in hotel room.

DAY 2: Pick-up by her patient manager, blood tests, first visit with rheumatologist, first rehabilitation session, first infusions. In the afternoon the patient did the Dexa-Scan. Light therapy and biophysical treatment in hotel room.

DAY 3: Pick-up by her patient manager, meeting with the Nutritionist Doctor, second infusions. In the afternoon she visited Verona with her patient manager and was able to walk a bit. Light therapy and biophysical treatment in hotel room.

DAY 4: Rest day in contact with her patient manager. Light therapy and biophysical treatment in hotel room.

DAY 5: Pick-up by her patient manager, third infusions and in the afternoon visit of Sirmione and Garda Lake. Light therapy and biophysical treatment in hotel room.

DAY 6: Pick-up by her patient manager, second visit with the rheumatologist, second rehabilitation session, fourth infusions and session with the Nutritionist. Light therapy and biophysical treatment in her room.

DAY 7: Rest day, in contact with her patient manager. The patient feels a bit sick and tired. Light therapy and biophysical treatment in her hotel room.

DAY 8: Light therapy and biophysical treatment in her hotel room. Pick-up by her patient manager, check out from Verona hotel and check in at Venice hotel. The patient feels much better, and she enjoys the touristic day with the gondola ride.

DAY 9: Pick-up by her patient manager, check out and drop off Venice airport for her flight back home.

Follow up

JUNE 2024 (2 months post-treatment): the patient reports small improvements.

JULY 2024 (3 months post-treatment): the patient is experiencing further improvements, and she is now able to walk longer distances. She is positive and trustful towards additional improvements over the next months.

Ongoing follow-up

Conclusion

The 6 months following the infusions are extremely important. A positive point of view, healthy diet, exercise, and general healthier lifestyle is key in helping the Neridronate help you.
This patient has been following the new anti-inflammatory diet advised by her nutritionist and mentions seeing a real difference.
Her initial results are positive, and we will hopefully see continuity in the improvements for this young woman.

DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.