CRPS Treatment: pain in left knee for 11 months

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CRPS Treatment: pain in left knee for 11 months

Contents

General details and patient's info

Gender:Male.
Age:40 years old at the time of treatment.
Home Country:USA.
Illness duration:11 months prior to the Neridronate Treatment.
Cause:Knee surgery.
Symptoms:Unbearable burning pain, swelling, stiffness, knee turns purple. Short walks are possible with crutches and help. Anything touching the leg is incredibly painful.
Clinical evaluation:CRPS diagnosis.
Time of treatment:November 2021.

Why the Patient decided to undergo the CRPS Treatment in Italy

This gentleman was a professional golf player. After a first surgery causing his CRPS, he was advised to undergo a second knee surgery to “fix the problem”. Obviously, it was not successful. At this point he did not trust the Doctors following him in California and refused any other option they offered. He decided to travel to Italy with the main goal of practicing golf again.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)
4 Pantoprazole infusions; Paracetamol.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep)
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Daily Report

DAY 1: Arrival at the Venice airport, greeted by his Patient Manager and check-in at the Vicenza Hotel. Light therapy and biophysical treatment have been installed in his hotel room; his Patient Manager has explained all details on how to operate the machines and on the following days program.

DAY 2: Rest day in contact with his Patient Manager. Light therapy and biophysical treatment in hotel room.

DAY 3: Morning pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor and 1st Neridronate infusion. In the afternoon short walk in Verona center. Light therapy and biophysical treatment in his hotel room.

DAY 4: Morning pick-up by his Patient Manager, 2nd Neridronate infusion. Visit to Vicenza’s City center. The patient feels very tired and needs to rest. Light therapy and biophysical treatment in his hotel room.

DAY 5: The patient still feels tired and has a light fever. The Rheumatologist Professor prescribes some Paracetamol. Light therapy and biophysical treatment in his hotel room.

DAY 6: Morning pick-up by his Patient Manager and 3rd Neridronate infusion. After the previous rest day, the patient feels better. Light therapy and biophysical treatment in his hotel room.

DAY 7: Morning pick-up by his Patient Manager, 2nd visit with the Rheumatologist Professor and 4th Neridronate infusion. The patient feels much better, in the afternoon he visits Soave with his Patient Manager. Light therapy and biophysical treatment in his hotel room.

DAY 8: Rest day in contact with his Patient Manager. He feels well and he goes shopping in Vicenza. Light therapy and biophysical treatment in hotel room.

DAY 9: Morning pick-up by his Patient Manager, check-out at hotel and drop-off at Venice airport to fly back home.

Follow up

DECEMBER 2021 (1 month after treatment): the patient experienced some small improvements; he still feels pain, but he says he can feel it changing and he feels confident.

FEBRUARY 2022 (3 months after treatment): the patient is doing well, pain lowered to bearable levels. He can now touch his leg without being in pain.

APRIL 2022 (5 months after treatment): pain levels are decreasing drastically, and the patient does not need his crutches anymore.

AUGUST 2022 (9 months after treatment): the patient went into full remission. He started practicing golf few weeks ago!

Conclusion

This was a very successful case; this patient had been suffering with CRPS for 11 months and was restricted to using crutches most of the time. His allodynia was intense and made it difficult even wearing trousers. 6 months after the treatment, the patient was confirming a full remission of all symptoms, which slowly manifested during the months after the treatment.
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.