CRPS Treatment: pain in right foot and ankle for 4 years

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CRPS Treatment: pain in right foot and ankle for 4 years

Contents

General details and patient's info

Gender:Female.
Age:47 years old at the time of treatment.
Home Country:Australia.
Illness duration:4 years prior to the Neridronate Treatment.
Cause:Right foot fracture in a boat accident.
Symptoms:Sharp pain worse on the foot; electric shocks; temperature change, sweating, color change; worsen upon walking long distances; pain is worse at night.
Clinical evaluation:CRPS. The patient meets the Budapest Criteria. Atrophy to the muscles in the right midcalf with a decrease in circumference.
Time of treatment:April 2020.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient found us looking through Chronic pain forums online. Someone had mentioned having CRPS and the fact that they were looking at the program in Italy. In March, this patient then contacted us to start her own process, and we welcomed her a month later.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

3 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

Daily Report

DAY 1: Arrival at Venice airport with her husband, welcomed by her Patient Manager; check in at Verona hotel and rest.

DAY 2: Morning pick-up by her Patient Manager, 1st visit with the Rheumatologist Professor, 1st infusions, 1st rehabilitation session.

DAY 3: Morning pick-up by her Patient Manager and 2nd infusions. Her husband being an architect, he specifically requested to do one of their touristic afternoons in Vicenza, to discover the architectural art of Palladio.

DAY 4: Morning pick-up by her Patient Manager and 3rd infusions, 2nd rehabilitation session. Patient feels a bit tired and achy. Doctor gives her paracetamol to help.

DAY 5: Rest day in contact with her Patient Manager. Patient feels better.

DAY 6: Morning pick-up by her Patient Manager and 3rd infusions. Tourism in Verona.

DAY 7: Morning pick-up by her Patient Manager, last visit with the Rheumatologist Professor, 3rd rehabilitation session and last infusions.

DAY 8: Rest day in contact with her Patient Manager.

DAY 9: Early pick-up from her Patient Manager, check out and drop off at Venice airport.

Follow up

JULY 2020 (3 months after the Neridronate treatment): the patient started to feel improvements about a month ago. Her pain levels have gone down, and the swelling has improved too.

NOVEMBRE 2020 (7 months after the Neridronate treatment): patient reports a general improvement of symptoms of 70%, with the swelling being completely gone. She can now walk longer distances and use her foot much more than before the treatment. She even was able to wear heels for a few nights!

MAY 2022 (2 years after the Neridronate treatment): the patient confirms her improvements are lasting, and she has now gotten back to her old self, restarting a lot of the activities she had to stop because of the pain.

Conclusion

This case shown really good results: after 4 years of suffering with unbearable pain daily, and not being to use her foot more than a few minutes, this patient finally regained mobility and saw a 70% improvement of all her symptoms, with the swelling completely disappearing after 5 months.
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.