CRPS Treatment: pain in right foot and lower leg for 1 year

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CRPS Treatment: pain in right foot and lower leg for 1 year

Contents

General details and patient's info

Gender:Male.
Age:46 years old at the time of treatment.
Home Country:USA.
Illness duration:1 year prior to the Neridronate Treatment.
Cause:Achilles tendon injury.
Symptoms:Excessive sweating of the foot, shooting and tingling pain, leg muscle cramps. Hair loss and extreme sensitivity to any touch. Walking, driving, wearing shoes increase the pain.
Clinical evaluation:CRPS type II. Pain very poorly controlled with pain medications. Pain is 5-6 on 10.
Time of treatment:December 2018.

Why the Patient decided to undergo the CRPS Treatment in Italy

It was the patient’s doctor, after all the other options had been ineffective, to advise him to look into the Neridronate treatment. Together they researched this option and quickly contacted us to organize his treatment week.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Pantoprazole infusions; Paracetamol.

2 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

7 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

Daily Report

DAY 1: Arrival at Venice airport with his wife, welcomed by his Patient Manager; check in at Verona hotel.

DAY 2: Pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor, 1st Rehabilitation session, 1st infusions.

DAY 3: Pick-up by his Patient Manager and 2nd infusions. In the afternoon, trip to Garda Lake and dinner in a typical restaurant. The patient is doing well, he does not experience any side effects.

DAY 4: Morning pick-up by his Patient Manager, 2nd Rehabilitation session and 3rd infusions. Visit of Vicenza’s center. In the evening, the patient feels a bit tired.

DAY 6: Morning pick-up by his Patient Manager, 2nd visit with the Rheumatologist Professor and 4th infusions. In the afternoon he visits Verona with the Patient Manager.

DAY 7: Pick up by his Patient Manager, check out Verona hotel and check in at Venice Hotel. In the afternoon visit of Venice and gondola ride.

DAY 8: Rest day in Venice, in contact with his Patient Manager.

DAY 9: Pick-up from his Patient Manager, check out and drop off to Venice airport.

Follow up

JANUARY 2019 (1 months after the Neridronate treatment): the patient feels stronger but there are no changes in pain levels.

MARCH 2019 (3 months after the Neridronate treatment): the patient reports a small reduction of pain. Driving is not as painful anymore.

MAY 2019 (5 months after the Neridronate treatment): the patient feels much better, he can easily stand and manage the pain. He can sleep better at night, and he is walking every day.

JULY 2019 (7 months after the Neridronate treatment): the patient is completely back to all his activities and daily duties. He rates his pain at level 1, sometimes 2.

Conclusion

CRPS is unfortunately still unknown by most medical professionals. Very often it is the patient that takes the time to search information about it. In this case the patient’s doctor was very helpful, suggesting him to travel to Italy. Spreading information is important, especially among the medical professional community. This would help to receive quicker diagnosis and timely support. It is important to underline that Neridronate is much more effective when taken at the disease early stages. This patient had a really good outcome and can finally get back to his normal life.
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.