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CRPS Treatment: pain in right foot for 8 years

General details and patient's info

Gender:Male.
Age:56 years old at the time of treatment.
Home Country:U.S.A.
Illness duration:8 years prior to the Neridronate Treatment.
Cause:Sprained ankle.
Symptoms:Stabbing sharp pain; cannot put weight on the right foot; too swollen to wear a shoe on the affected foot; sensitivity to weather change.
Clinical evaluation:CRPS. 
Time of treatment:September 2022.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient knew about Neridronate but as initially too scared to fly, as he had never been in a plane before. When COVID ended, he decided he wanted to undergo the treatment and got the courage to take a place for the first time.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

3 sessions Neuromuscular Rehabilitation Treatment Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep)
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Daily Report

DAY 1: Arrival at the Venice airport, greeted by his Patient Manager, followed by check-in at his Hotel in Verona. Briefing focused on the next days.

DAY 2: Rest day in the hotel, in contact with his Patient Manager.

DAY 3: Morning pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor, 1st Rehabilitation session, and 1st infusions.

DAY 4: Morning pick-up by his Patient Manager, 2nd infusions.

DAY 5: Morning pick-up by his Patient Manager, 2nd Rehabilitation session and 3rd infusions.

DAY 6: Rest day in the hotel, in contact with his Patient Manager. Tourism in Verona.

DAY 7: Morning pick-up by his Patient Manager, 3rd Rehabilitation session, 4th infusions and 2nd visit with the Rheumatologist Professor.

DAY 8: Sightseeing in Venise with his Patient Manager.

DAY 9: Pick-up by his Patient Manager, check-out, and drop-off at the Venice airport for his trip back home.

Follow up

DECEMBER 2022 (3 months after Neridronate treatment): The patient says it is easier to put weight on the affected foot, the swelling has lowered, and the pain is definitely improving.

MARCH 2023 (6 months after Neridronate treatment): Patient refers to an improvement of the pain of about 60%, he is able to wear shoes on the affected foot now and manages to walk about an hour without any kind of aid.

Conclusion

The patient came to Italy with the impossibility to wear shoes or bare weight on the affected foot. 6 months later both those became possible for the patient, who also now lives with 60% of daily pain.

DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.