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CRPS Treatment: pain in right hand and arm for 9 months

General details and patient's info

Age:22 years old at the time of treatment.
Home Country:USA.
Illness duration:9 months prior to the Neridronate Treatment.
Cause:Fell and broke his arm.
Symptoms:Sharp pain; muscle spasms; change of color; burning sensation.
Clinical evaluation:CRPS. 
Time of treatment:March 2021.

Why the Patient decided to undergo the CRPS Treatment in Italy

The patient’s mother is the one who found us online, she was looking for treatments against CRPS and she read the original study which stated that it currently is the best option for CRPS fighters and decided to contact us shortly after. We welcomed her and her son a month later. 

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

3 sessions Neuromuscular Rehabilitation Treatment Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

8 nights Biophysical Treatment (5 hours each night while the patients are asleep)
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Daily Report

DAY 1: Arrival at the Venice airport, greeted by his Patient Manager, followed by check-in at his Hotel in Verona. Briefing focused on the next days.

DAY 2: Rest day in the hotel, in contact with his Patient Manager.

DAY 3: Morning pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor, 1st Rehabilitation session, and 1st infusions.

DAY 4: Morning pick-up by his Patient Manager, 2nd infusions. Tourism in Verona.

DAY 5: Rest day in the hotel, in contact with his Patient Manager.

DAY 6: Morning pick-up by his Patient Manager, 2nd Rehabilitation session and 3rd infusions. Tourism in Verona.

DAY 7: Morning pick-up by his Patient Manager, 3rd Rehabilitation session, 4th infusions and 2nd visit with the Rheumatologist Professor. Tourism in Sirmione.

DAY 8-9: Rest days in the hotel, in contact with his Patient Manager.

DAY 10: Pick-up by his Patient Manager, check-out, and drop-off at the Venice airport for his trip back home.

Follow up

JUNE 2021 (3 months after Neridronate treatment): The patient says he only feels a light improvement of his pain levels but nothing too noticeable. The color changes have disappeared, however.

SEPTEMBER 2021 (6 months after Neridronate treatment): The patient refers to a 90% improvement of his symptoms.

NOVEMBER 2021 (8 months after Neridronate treatment): The patient confirms a 90-95% improvement of his condition, with the occasional flare up that is however much more manageable that it used to.


Undergoing the treatment within the first year od the condition is always the best condition, it can sometimes lead to remission, or as in this case, a 90-95% improvement of the condition.

This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.