CRPS Treatment: pain in right hand and arm leg for 19 years

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CRPS Treatment: pain in right hand and arm leg for 19 years

Contents

General details and patient's info

Gender:Female.
Age:65 years old at the time of treatment.
Home Country:USA.
Illness duration:19 years prior to the Neridronate Treatment.
Cause:Surgery for carpal tunnel syndrome.
Symptoms:Sensation of scrubbing with sandpaper; crushed bones feeling; extremely painful at any slightest touch. Very weak, not able to hold a pen, a fork or any object: impossible to perform daily routine activities by herself, help needed also for personal hygiene. Occasionally right arm has muscle spasms.
Clinical evaluation:CRPS.
Time of treatment:December 2021.

Why the Patient decided to undergo the CRPS Treatment in Italy

CRPS totally affected the patient life; the excruciating pain made impossible for her to work, to manage her house and take care of her family of 4. It took her over 10 years to receive the diagnosis from a pain specialist doctor who finally suggested a spinal cord stimulator. She had a great relief from it, but still the pain level never went below 7. Exhausted from her long-lasting condition she decided to try Neridronate in Italy.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 Neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

4 Pantoprazole infusions; Paracetamol.

3 sessions Rehabilitation Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

9 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

9 nights Biophysical Treatment (5 hours each night while the patients are asleep)
MTI’s Biophysical Treatment is the outcome of 25 years of research and studies. It has been certified by the best Italian Universities, partners from both public and private teams. The Biophysical treatment acts on the roots of the disease, brings relief to the inflammatory condition, helps the cells regeneration, the oxygenation, the micro-circulation, and the lymphatic system.

Daily Report

DAY 1: Arrival at Venice airport, welcomed by the dedicated patient manager, drive to Verona, check in at Verona hotel. The patient is very tired and in great pain. Light therapy and biophysical therapy in hotel room.

DAY 2: Rest day, in contact with her patient manager. Light therapy and biophysical therapy in hotel room.

DAY 3: Pick-up from her patient manager, first visit with the Rheumatologist Professor, 1st Rehabilitation session and first infusions. The patient is still very tired from her long flight and wishes to rest. Light therapy and biophysical therapy in hotel room.

DAY 4: Pick-up from her patient manager, second infusions. The Rheumatologist doctor prescribes Tylenol to manage a light fever and discomfort. Light therapy and biophysical therapy in hotel room.

DAY 5: Pick-up from the patient manager, third infusions and 2nd Rehabilitation session. The patient is exhausted, so the Rheumatologist Professor advises a rest day to allow her some recovery. Light therapy and biophysical therapy in hotel room.

DAY 6: Rest day in contact with her patient manager. The patient spends it in her hotel room, resting and enjoying the light therapy which brings much relief to her hand.

DAY 7: Pick-up by her patient manager, second visit with the Rheumatologist Professor who prescribes supplements to help the lack of energy. 3rd Rehabilitation session and last infusions. Then light therapy and biophysical therapy in hotel room.

DAY 8: Rest day. In the afternoon the patient feels better, and she goes for a walk in Verona with her patient manager. Light therapy and biophysical therapy in hotel room.

DAY 9: Pick-up from the patient manager, check out and drop-off to Venice airport for the flight back home.

Follow up

MARCH 2022 (3 months after the Neridronate treatment): the patient says that she feels stronger, more comfortable during the day, and her mood is improving. She says that her pain level is about 6.

MAY 2022 (5 months after the Neridronate treatment): the patient says that she can see a reduction of her pain levels.

JUNE 2022 (6 months after the Neridronate treatment): the patient says that her daily pain levels have dropped to 4.

OCTOBER 2022 (9 months after the Neridronate treatment): the patient says that her pain never goes higher than 5 and is usually around 3-4. She can now manage several activities and take care of her own hygiene and personal needs.

DECEMBER 2022 (12 months after the Neridronate treatment): the patient confirms that her pain level keeps on a 4.

Conclusion

The patient was really happy of the treatment’s outcomes even though she still feels a bit of pain, reducing it greatly improved her life quality. Neridronate is much more effective if taken within 18/24 months from the CRPS onset. However, as in this case, it may bring a partial relief even after many years. It is always worth trying it.
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DISCLAIMER
This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.