Would you like to know if you are eligible for the Neridronate Treatment? Book your free video call now!

CRPS Treatment: pain in both arms for 1.5 year

General details and patient's info

Age:57 years old at the time of treatment.
Home Country:Australia.
Illness duration:1.5 year prior to the Neridronate Treatment.
Cause:Work injury, he got hit by debris during a machinery malfunction.
Symptoms:Burning pain; swelling; the hand often changes color to red or purple; sensitive to weather change.
Clinical evaluation:CRPS.
Time of treatment:June 2023.

Why the Patient decided to undergo the CRPS Treatment in Italy

He found us online after looking up treatment options out of state. He used to do woodwork, it was his favorite hobby and due to the pain and discomfort he had to stop. His life goal would be to be able to do everything that he used to do before the accident, to go back to work and not deal with the pain on a daily basis.

Medical treatment the Patient underwent in Italy

Complex regional pain syndrome (CRPS) is a severely painful and disabling disease for which a multitude of therapeutic interventions have been proposed. In the past two decades, only Bisphosphonates gained credibility. In recent years, more convincing evidence has become available on the use of Parenteral Neridronate. Since 2014, this drug is registered and marketed in Italy for the treatment of CRPS. To date, the only therapeutic schedule that is recognized to be able to confer benefit is the intravenous (IV) administration of 100 mg given 4 times.

4 neridronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

See the Official Study on the Oxford Academics website: https://academic.oup.com/rheumatology/article/52/3/534/1777330

4 Clodronate infusions (100mg, I.v. in saline Solution 0,9% 250 ml)

3 sessions Neuromuscular Rehabilitation Treatment Treatment with Physiotherapist.
Rehabilitation therapy is a full body workout which focuses on the general wellbeing of the body, to help the affected limb get back to its normal self.

8 days Light Therapy (in hotel room, 30+ more minutes each day)
30 minutes or more of usage of the MTI Light Therapy reduces inflammation, increase micro-circulation, relax nerves and muscles, reduces pain transmission, accelerates healing, regenerates cells, and promotes cells activation.

Daily Report

DAY 1: Arrival at the Venice airport, greeted by his Patient Manager, followed by check-in at his Hotel in Verona. Briefing focused on the next days.

DAY 2: Rest day in the hotel, in contact with his Patient Manager.

DAY 3: Morning pick-up by his Patient Manager, 1st visit with the Rheumatologist Professor, 1st Rehabilitation session, and 1st infusions.

DAY 4: Morning pick-up by his Patient Manager, 2nd infusions.

DAY 5: Rest day in the hotel, in contact with his Patient Manager.

DAY 6: Morning pick-up by his Patient Manager, 2nd Rehabilitation session and 3rd infusions.

DAY 7: Morning pick-up by his Patient Manager, 3rd Rehabilitation session, 4th infusions and 2nd visit with the Rheumatologist Professor.

DAY 8: Rest day in the hotel, in contact with his Patient Manager.

DAY 9: Pick-up by his Patient Manager, check-out, and drop-off at the Venice airport for his trip back home.

Follow up

SEPTEMBER 2023 (3 months after Neridronate treatment): the patient says that he does not feel as much pain in his arms, he is able to lift them above his head. The color has gone back to normal.

NOVEMBER 2023 (5 months after Neridronate treatment): The patient mentions being in almost complete remission. He says that he does not experience pain anymore, only on some rare days, and that his arms look as they did before the accident.

JANUARY 2024 (7 months after Neridronate treatment): The patient is in complete remission. He mentions starting a new job after not being able to work for over a year and a half. He is back to woodworking and could not be happier to share with us his new creations!


For a patient to reach complete remission it is always amazing news, in particular someone who has had CRPS for almost 2 years like this patient. Doctors had high hopes for him from the beginning and he was the happiest when he saw improvements week after week. The best part for him was being able to go back to how his life was before it all happened. To leave the bad days behind was his biggest achievement.

This is not a medical case study; it merely describes each patient’s journey, and it omits all personal data. The people who redacted it are not doctors but all the facts reported are objective and represent the patient’s reality thanks to the information in our possession. The report is not part of any clinical trials. It was written to provide more information to patients who have made multiple requests for treatment outcomes of cases like theirs.